Welcome to MedicalMagzine.org
Background To retrospectively analyze computed tomography (CT) features of adenosquamous carcinoma (ASC) of the extrahepatic bile duct and to correlate them with pathologic findings. Methods Six patients who underwent radical surgical resection for ASC of extrahepatic bile duct were included. CT and pathologic findings were analyzed and correlated with each other. Results Five ASCs were periductal infiltrative type and the remaining one was intraductal polypoid type. Histologically, ASC was composed of squamous and glandular components which mixed in an intermingled pattern and was characterized by a high local aggressiveness mainly due to the squamous component. The most common CT findings were a segmental wall thickening with delayed enhancement. Overall, CT features were well correlated with pathologic findings. However, CT tended to underestimate radial extent of the tumor compared with histologic findings. Conclusions Histopathologically, ASC of the extrahepatic bile duct is characterized by greater local aggressiveness. However, their CT findings are not quite different from those of usual adenocarcinoma due to the unique geographic characteristic of being located at a very limited space.
Kyung Won Kim1 Se Hyung Kim1 Min A. Kim2 Jeong Min Lee1 Hee Sun Park1 Ji Young Kim1 Jae Young Lee1 Joon Koo Han1 Byung Ihn Choi1
[1] Department of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, 28 Yeongon-dong, Jongno-gu, Seoul, 110-744, Korea;[2] Department of Pathology, Seoul National University Hospital, 28 Yeongon-dong, Jongno-gu, Seoul, 110-744, Korea